U.S. Covid cases have hit their highest level of the pandemic as two highly infectious variants circulate throughout the country and health officials urge Americans to get vaccinated and boosted against the virus.

Nationwide daily cases are at a record seven-day average of more than 265,000 as of Tuesday, according to data compiled by Johns Hopkins University, surpassing the previous high mark of about 252,000 average daily cases set on Jan. 11, 2021.

The new pandemic peak comes as the delta and omicron variants are spreading simultaneously. The previously dominant delta variant was already driving U.S. case counts higher this fall before the emergence of omicron, which is contributing to a near-vertical rise in daily new cases.