Vaccines Bringing Back a Nearly Eradicated Deadly Virus

Many people thought that the poliovirus was extinct across the majority of the world, as the World Health Organization (WHO) has declared many continents polio-free.

So this may come as a surprise, but in fact, polio cases have been on the rise globally since 2016, and this resurgent outbreak is related to the use of vaccines.
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On July 21, 2022, the first polio case in almost one decade was reported by the New York State Department of Health. And this case was also related to a vaccine-derived poliovirus strain. Poliovirus is non-enveloped. It is an enterovirus composed of a single stranded RNA and a protein shell.

Roughly 3 in 4 people infected with polio are asymptomatic. Even if there are symptoms, they usually resemble those of a flu. Yet in 1 percent of all polio cases, polio causes flaccid paralysis or disability, and it even can lead to death. This is then called paralytic poliomyelitis.

After contracting spinal paralytic poliomyelitis, 25 percent to 40 percent of patients will develop varying degrees of sequelae up to 15 to 40 years later, which are also known as “post-polio syndrome.”